Washington University in St Louis, St Louis, MO, USA
Jorge J. Llibre-Guerra, Nelly Joseph-Mathurin, Yan Li, Andrew J. Aschenbrenner, Cyril Pottier, Wendy Sigurdson, Eric McDade, Brian A. Gordon, Tammie L. S. Benzinger, Laura Ibañez, Nico Barthelemy, Matthew Johnson, Jason Hassenstab, Guoqiao Wang, Dan Western, Ciyang Wang, Diana Hobbs, Alisha Daniels, Celeste Karch, John C. Morris, Carlos Cruchaga, Randall J. Bateman, Bryce Baker, Jessica Banks, Nicolas R. Barthélemy, Jamie Bartzel, Randall Bateman, Allison Chen, Charles Chen, Laura Courtney, Alisha J. Daniels, Anne M. Fagan, Shaney Flores, Erin Franklin, Manu Goyal, Emily Gremminger, Cortaiga Hellm, David M. Holtzman, Russ Hornbeck, Laura Ibanez, Kelley Jackson, Gina Jerome, Celeste M. Karch, Sarah Keefe, Deborah Koudelis, Ruijin Lu, Jacob Marsh, Mariana Martin, Parinaz Massoumzadeh, Austin McCullough, Nicole McKay, Matthew Minton, Joyce Nicklaus, Yuzheng Nie, Richard J. Perrin, Christine Pulizos, Jacqueline Rizzo, Edita Sabaredzovic, Jalen Scott, Ashlee Simmons, Karina Skrbec, Jennifer Smith, Jennifer Stauber, Sarah Stout, Charlene Supnet-Bell, Andrei Vlassenko, Qing Wang, Yong Wang, Chengjie Xiong, Xiong Xu, Jinbin Xu, Angela Ziegemeier & Ellen Ziegemeier
Research Center and Memory Clinic, Fundació ACE Institut Català de Neurociències Aplicades – Universitat Internacional de Catalunya (UIC), Barcelona, Spain
M. Victoria Fernandez
Emory University School of Medicine, Atlanta, GA, USA
Shijia Bian & Kathleen Carter
Ronald M. Loeb Center for Alzheimer’s Disease, Dept of Genetics and Genomic Sciences, and Nash Family Dept of Neuroscience, Icahn School of Medicine at Mount Sinai, New York, NY, USA
Alan E. Renton, Alison M. Goate, Erik C. B. Johnson, Brian Fulton-Howard & Danielle M. Picarello
Grupo de Neurociencias de Antioquia (GNA), Facultad de Medicina, Universidad de Antioquia, Medellín, Colombia
David Aguillon, Ana Baena, Yamile Bocanegra, Yudy Milena Leon, Francisco Lopera, Laura Ramirez & Laura Serna
Institute for Neurological Research Fleni, Buenos Aires, Argentina
Ricardo F. Allegri, Patricio Chrem Mendez, Ezequiel Surace & Silvia Vazquez
Neuroscience Research Australia, Sydney, New South Wales, Australia
Jacob A. Bechara, William S. Brooks, Emma Devenney & Peter R. Schofield
University of Pittsburgh, Pittsburgh, PA, USA
Sarah B. Berman & Snezana Ikonomovic
Dementia Research Centre, UCL Queen Square Institute of Neurology, London, UK
David M. Cash, Nick C. Fox & Natalie S. Ryan
Massachusetts General Hospital, Brigham and Women’s Hospital, Harvard Medical School, Boston, MA, USA
Jasmeer P. Chhatwal & Courtney Maa
Mayo Clinic in Florida, Jacksonville, FL, USA
Gregory S. Day & Neill R. Graff-Radford
Indiana University, School of Medicine, Bloomington, IN, USA
Martin Farlow
German Center for Neurodegenerative Diseases (DZNE), Tübingen, Germany
Susanne Graber-Sultan, Mathias Jucker, Elke Kuder-Buletta, Christian la Fougère, Christoph Laske, Ulrike Obermueller, Gerald Reischl & Reda Timofejavaite
Goizueta Alzheimer’s Disease Research Center, Emory University, Atlanta, GA, USA
Edward D. Huey, Allan I. Levey, Stephen Salloway & Nicholas T. Seyfried
Brain Research Institute, Niigata University, Niigata, Japan
Takeshi Ikeuchi, Takanobu Ishiguro & Kensaku Kasuga
Tokyo Metropolitan Institute of Gerontology, Tokyo, Japan
Kenji Ishii
Korea University College of Medicine, Seoul, Republic of South Korea
Jae-Hong Lee & Jee Hoon Roh
German Center for Neurodegenerative Diseases, Munich, Munich, Germany
Johannes Levin, Yvonne Rödenbeck & Jonathan Vöglein
Edith Cowan University, Perth, Western Australia, Australia
Ralph Martins
Florey Institute, The University of Melbourne, Melbourne, Victoria, Australia
Colin Masters
Osaka Metropolitan University, Osaka, Japan
Hiroshi Mori
The University of Tokyo Hospital, Tokyo, Japan
Yoshiki Niimi
Taub Institute for Research on Alzheimer’s Disease and the Aging Brain, Columbia University Irving Medical Center, New York, NY, USA
James M. Noble
Department of Neurology, Keck School of Medicine of USC, University of Southern California, Los Angeles, CA, USA
John Ringman
McGill University, Montreal, Quebec, Canada
Pedro Rosa-Neto
University of Barcelona, Barcelona, Spain
Raquel Sanchez-Valle
Kobe City Medical Center General Hospital, Kobe, Japan
Michio Senda
J.J.L.-G. and R.J.B. initiated this work, supervised the study and drafted the manuscript. J.J.L.-G., A.J.A., E.M. and W.S. collected and analyzed the clinical and phenotypic data. N.J.-M., B.A.G., T.L.S.B. and D.H. collected and analyzed the imaging data. M.V.F., C.P., M.J., A.E.R., A.M.G. and C.C. contributed to the genetic analyses and data interpretation. S.B., K.C., M.V.F., D.W., C.W. and E.C.B.J. conducted and analyzed the proteomic studies. L.I., N.B., J.J.L.-G. and R.J.B. assisted with molecular and biomarker data collection and analysis. All authors contributed to reviewing the manuscript and refining data analysis. J.J.L.-G. had direct access to and verified the data reported in the manuscript. J.J.L.-G., M.V.F. and N.J.-M. are first authors and contributed equally. C.C., E.C.B.J. and R.J.B. are senior authors and jointly supervised this work.
